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Neurons that tell you to stop eating could unlock obesity treatments | Researchers have identified the specific neurons in mice brains that tell them they've eaten enough. This discovery could play a big role in the future of weight loss treatments for humans.
Researchers at Columbia University Irving Medical Center have identified the specific neurons in mice brains that tell them they've eaten enough. This fascinating discovery could play a big role in the future of weight loss treatments for humans.
Specifically, as the researchers noted "... a population of neuropeptidergic neurons in the brainstem’s dorsal raphe nucleus (DRN)" in their paper published in the journal Cell. "These neurons track food from sensory presentation through ingestion, integrate these signals with slower-acting humoral cues, and express cholecystokinin (CCK)," revealed the team. The study's identification of CCK neurons as a key component of the satiation circuitry provides a potential mechanism for understanding how GLP-1 agonists achieve this effect.
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