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New 3D bioprinting technique may improve production of engineered tissue


New method developed by engineers from MIT and Politecnico di Milano Polimi enhances 3D bioprinting capabilities, accelerating process optimization‎ for real-world applications in tissue engineering.

To date, one of the most-used approaches for bioprinting relies on additive manufacturing techniques and digital models, depositing 2D layers of bio-inks, composed of cells in a soft gel, into a support bath, layer-by-layer, to build a 3D structure. The need motivated Raman to collaborate with Tolga Durak at MIT's Safety, Health, Environmental Discovery Lab ( The SHED) and seek the expertise of Professor Bianca Colosimo of the Polytechnic University of Milan, also known as Polimi. "These capabilities will be immediately utilized for fabricating the bio-printed scaffolds and vascularized constructs to cultivate microphysiological systems (MPS) and large-scale liver organoids in our current research project," says Durak, highlighting the significance of this process optimization.

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