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New & old drug combo drops cholesterol by 49% in human trial


Some people can’t get their bad cholesterol levels down, even if they take cholesterol-lowering meds. A new clinical trial using a combination of existing and not-yet-released cholesterol tablets lowered bad cholesterol by almost half in people at high risk of heart disease.

We understand how high levels of low-density lipoprotein(LDL or “bad”) cholesterol can lead to plaque buildup on arteries, increasing the risk of a heart attack or stroke. “This combination therapy [we studied] helped high-risk patients who need additional LDL cholesterol lowering to potentially reach their goals.” “These results support the potential of using this fixed dose combination to help treat an often difficult-to-treat patient population,” said Steven Nissen, MD, Chief Academic Officer of the Heart, Vascular and Thoracic Institute at the Cleveland Clinic and the study’s corresponding author.

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