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New "smart capsule" to study the health of the GI tract
PillTrek offers a swallowable way to monitor a variety of biomarkers in the complex environment of the gut
Traditional evaluation methods involve either fecal analysis or biopsy, which are invasive, expensive, and cannot provide real-time profiling across the GI tract. As a proof of concept, PillTrek was used in the study to measure pH and temperature as well as changing levels of glucose and the neurotransmitter serotonin in animal models. Additional authors of the paper are Heather Lukas (MS '21), Xiaotian Ma, Rinni Bhansali, Sung-Hyuk Sunwoo, Canran Wang (MS '23), Yadong Xu, Dickson R. Yao, and Gwangmook Kim of Caltech, as well as Zhaoping Li and Tzung K. Hsiai of the David Geffen School of Medicine at UCLA and Hee-Tae Jung of KAIST.
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