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New biomaterial regrows cartilage; could prevent knee replacement surgery


The team applied this material to the damaged knee cartilage of sheep and observed significant repair improvements within a six-month period.

This research builds on previous work from the Stupp laboratory, which involved using “dancing molecules” to stimulate human cartilage cells to increase the production of tissue matrix proteins. Stupp’s team combined a bioactive peptide with chemically modified hyaluronic acid particles to create nanoscale fiber bundles that mimic cartilage structure. With further development, researchers believe this new material could potentially prevent the need for full knee replacements, treat degenerative diseases like osteoarthritis, and repair sports-related injuries such as ACL tears.

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