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New wearable tech could help track PTSD, sepsis early through nerve activity | This technology could enable doctors to pinpoint patients who are at increased risk of excessive immune responses or immunoparalysis.


The device captures what the researchers term Autonomic Neurography, which Includes neural activity from the vagus and carotid sinus nerves.

To provide medical professionals with a real-time, clinically proven tool for detecting levels of activity in the involuntary nervous system—an early indicator of bodily stress—the researchers designed a flexible, adhesive-integrated electrode array in 2022. Acting as a critical conduit within the autonomic nervous system, the vagus nerve extends from the base of the skull through the torso and abdomen, impacting functions such as digestion, heart rate, and immune responses. The researchers tracked variations in heart rate and observed a significant correlation between nerve firing at both monitoring sites and fluctuations in two key inflammatory cytokines: tumor necrosis factor-alpha (TNF-α) and interleukin-10 (IL-10).

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