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No more injections: MIT develop capsule that delivers drugs straight to the gut | This capsule is designed to release drugs directly into the stomach wall or other organs in the digestive tract.
MIT has developed an ingestible capsule inspired by squid propulsion, delivering drugs directly to the stomach without needles.
Traditional oral delivery methods for drugs composed of large proteins or RNA are ineffective because these molecules tend to degrade in the digestive system. In their experiments, the researchers calculated the necessary pressures to expel drugs forcefully enough to penetrate the submucosal tissue, forming a depot that gradually releases the medication. One version, shaped like a blueberry, features a flat bottom and a high dome, allowing it to rest on the stomach lining and eject drugs downward into the tissue.
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