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Osteoarthritic knee pain reduced by non-invasive application of in-ear electrical stimulation to the vagus nerve | This procedure opens the door to innovative, quality-of-life-improving treatment.


A new study has found the non-invasive application of in-ear electrical stimulation to the vagus nerve to be safe and effective in reducing osteoarthritis-related knee pain. It opens the door to innovative, quality-of-life-improving treatment.

In a new study led by the University of Texas at El Paso (UTEP), researchers conducted a pilot trial to evaluate the effectiveness of non-invasive vagus nerve stimulation via the ear to treat osteoarthritis (OA)-related knee pain. It can be delivered using a device that sits on the ear and sends an electrical pulse to the auricular branch of the vagus nerve, which is found under the skin in the magenta area in the diagram below. “All of our participants completed the full 60-min tVNS protocol without any major side effects and >one-third exceeded the minimally clinically important threshold for knee pain improvement,” the researchers said.

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