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Parkinson's may begin in the gut, study says, adding to growing evidence
Mucosal damage — an erosion, break or sore in the mucous lining of the GI tract — was associated with a 76 percent greater risk of developing Parkinson’s.
Mucosal damage — an erosion, break, or sore in the mucous lining of the gastrointestinal tract — was associated with a 76 percent greater risk of developing Parkinson’s disease during the follow-up period, an average of 14.9 years for the whole cohort. When the gut-first hypothesis “first came out, there was a lot of skepticism in the field,” said Ted M. Dawson, Leonard and Madlyn Abramson professor in neurodegenerative diseases at Johns Hopkins University School of Medicine, who was not involved in the study. A previous version of this article included a quotation from Delaram Safarpour, an associate professor of neurology at Oregon Health & Science University, that implied that people who have a history of mucosal damage could be treated for Parkinson's disease before they have motor symptoms.
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