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Pig lung transplanted into a human


A genetically modified pig lung transplanted into a brain-dead human patient functioned for nine days in a new achievement that reveals both the promise and significant challenges of xenotransplantation.

It's the first time a pig lung has been transplanted into a human patient, demonstrating a significant step forward, and giving scientists new problems to solve as they develop this emerging medical technique further. "The early onset of pulmonary edema underscores the importance of preventing primary graft dysfunction in future xenogeneic lung transplantation," the researchers write in their paper. "Continued efforts are needed to optimize immunosuppressive regimens, refine genetic modifications, enhance lung preservation strategies and assess long-term graft function beyond the acute phase.

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