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Plaque-hunting nanoparticles detect and disarm the driver of heart disease | Researchers have engineered porphyrin-lipid nanoparticles that can identify artery build-up, break down the plaques and suppress inflammation
A new generation of “theranostic” nanoparticles has been shown to both detect and reduce plaques in the arteries. Nanoparticles absorbed by immune cells in the arteries, where they work to lower inflammation and draw out harmful cholesterol, offer an entirely new way of not just diagnosing but…
Nanoparticles absorbed by immune cells in the arteries, where they work to lower inflammation and draw out harmful cholesterol, offer an entirely new way of not just diagnosing but fighting heart disease without drugs. "One of the key challenges in treating atherosclerosis is that inflammation fuels plaque build-up, creating a vicious cycle," said study lead Dr Victoria Nankivell from SAHMRI. "What sets these nanoparticles apart is their ability to interact directly with immune cells in the arteries, drawing out cholesterol and helping the body process it more effectively," Nankivell said.
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