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Popular gut probiotic craps out in randomized controlled trial


If you’re familiar with the history of Activia, you may not be surprised.

Any striking marketing claims in companies' ads about the gut benefits of a popular probiotic may be full of, well, the same thing that has their target audience backed up. The study adds to a mixed and mostly unconvincing body of scientific literature on the bowel benefits of the bacterium, substrains of which are sometimes sold with faux scientific-sounding names in products. There was little change during the trial and no significant group differences in the moisture content of stools, or levels of short-chain fatty acids and calprotectin, a marker for intestinal inflammation.

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