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Psilocybin shows promise as anti-aging therapy


Psilocybin, the active compound derived from psychedelic mushrooms, significantly delayed cellular aging and extended lifespan in a preclinical study.

A newly published study in Nature Partner Journals’ Aging demonstrates that psilocin, a byproduct of consuming psilocybin, the active ingredient in psychedelic mushrooms, extended the cellular lifespan of human skin and lung cells by more than 50%. While traditionally researched for its mental health benefits, this study suggests that psilocybin impacts multiple hallmarks of aging by reducing oxidative stress, improving DNA repair responses, and preserving telomere length. “This study provides strong preclinical evidence that psilocybin may contribute to healthier aging– not just a longer lifespan, but a better quality of life in later years,” says Director of Psychedelic Research at Emory University’s Department of Psychiatry Ali John Zarrabi, MD.

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