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Psilocybin Treatment Extends Cellular Lifespan, Improves Survival of Aged Mice


A new study found that psilocybin treatment significantly delayed cellular aging, extending human cell lifespan by over 50% and increasing survival in aged mice by 30%. The compound appeared to achieve these effects by reducing oxidative stress, preserving telomeres, and improving DNA repair. Neuros...

Neuroscience News reports: A newly published study in Nature Partner Journals' Aging demonstrates that psilocin, a byproduct of consuming psilocybin, the active ingredient in psychedelic mushrooms, extended the cellular lifespan of human skin and lung cells by more than 50%. In parallel, researchers also conducted the first long-term in vivo study evaluating the systemic effects of psilocybin in aged mice of 19 months, or the equivalent of 60-65 human years. While traditionally researched for its mental health benefits, this study suggests that psilocybin impacts multiple hallmarks of aging by reducing oxidative stress, improving DNA repair responses, and preserving telomere length.

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