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Psilocybin treatment extends cellular lifespan, improves survival of aged mice
Emory University researchers identified that psilocin, a byproduct of consuming psilocybin, the active ingredient in psychedelic mushrooms, actively delays aging in cells and organisms.
A newly published study in Nature Partner Journals’ Aging demonstrates that psilocin, a byproduct of consuming psilocybin, the active ingredient in psychedelic mushrooms, extended the cellular lifespan of human skin and lung cells by more than 50%. While traditionally researched for its mental health benefits, this study suggests that psilocybin impacts multiple hallmarks of aging by reducing oxidative stress, improving DNA repair responses, and preserving telomere length. “This study provides strong preclinical evidence that psilocybin may contribute to healthier aging — not just a longer lifespan, but a better quality of life in later years,” says Ali John Zarrabi, MD, director of psychedelic research at Emory's Department of Psychiatry.
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