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Reproducibility project fails to validate dozens of biomedical studies
Unique reproducibility effort in Brazil focuses on common methods rather than a single field ― and prompts call for reform.
The scientists wanted to assess publications “based on methods, rather than research area, perceived importance or citation counts”, de Abreu says. They ended up selecting three of these methods: an assay of cell metabolism, a technique for amplifying genetic material and a type of maze test for rodents. Then the authors randomly selected biomedical papers that relied on those methods and were published from 1998 to 2017 by research teams in which at least half the contributors had a Brazilian affiliation.
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