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Research fueled by F1 legend and Dyson makes Alzheimer's strides | Using living tissue has revealed the brain's sweet spot for tau proteins.
An unusual partnership between a vacuum maker, a race car legend, and the University of Edinburgh is leading to advances in understanding dementia. Their new study using living tissue has revealed the brain's sweet spot for tau proteins.
As part of the research, the team also found that slices of brain tissue taken from the temporal lobe released high levels of another Alzheimer's-implicated protein: tau. Finding it in this brain region, which is associated with the formation of auditory and visual memories, could explain why the temporal lobe is particularly affected early in the disease's progression. The novel use of living tissue, say fellow collaborators, will allow more accurate development of dementia treatments as it can sidestep the use of animal models and speed up clinical trials of potentially life-and-cognition-saving drugs.
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