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Researchers find cancer's 'off-grid' power supply – and how to cut it | Researchers have discovered a particular type of cancer cell that relies on its own biological electric utility. Disrupting the utility with the help of a puffer fish – showed a breakthrough way to fight the tumors.
Researchers have discovered a particular type of cancer cell that relies on its own biological electric utility company to thrive. Disrupting this power plant – with the help of a puffer fish – showed a breakthrough way to fight the tumors.
Now, researchers from the Francis Crick Institute (FCI) have discovered that some of the cells involved with the formation of SCLC tumors demonstrate high levels of electrical activity. Sure enough, while the tetrodotoxin didn't kill the electricity-producing NE cells, it did reduce their potential to form tumors long-term, showing that interrupting the electrical activity of SCLC could be a powerful, breakthrough way to fight the disease. "There’s still a long way to go to understand the biological impact of this electrical activity and the specific disease mechanisms that make the tumor more aggressive and harder to treat," said Li.
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