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Researchers have created a new vaccine candidate to treat staph and antibiotic-resistant MRSA infections. In mouse studies, the new candidate offered high immunity to otherwise lethal levels of Staphylococcus aureus, or staph, and methicillin-resistant S. aureus, or MRSA.


MSU, Harvard Medical School team up to expand vaccine science’s role in the fight against MRSA and other infections

“There are worries that at the rate things are going, in perhaps 20 or 30 years, few of our drugs will be effective at all,” said Xuefei Huang, a Michigan State University Research Foundation Professor in the departments of Chemistry and Biomedical Engineering. Gerald Pier, professor of medicine at Harvard Medical School and Brigham and Women’s Hospital and a collaborator on the latest MSU-led paper, has studied one such antigen candidate for years. PNAG and other carbohydrates typically don’t provoke strong immune responses in our bodies, but the mutant Qbeta, or mQβ, helps create an enhanced reaction.

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