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Researchers have discovered that newborns have high levels of the tau protein, which is elevated in older people with Alzheimer’s disease, but that it causes them no harm | The discovery opens the door to developing new ways of treating or preventing the neurodegenerative condition.


Researchers have discovered that newborns have high levels of the tau protein, which is elevated in older people with Alzheimer’s disease, but that it causes them no harm. The discovery opens the door to developing new ways of treating or preventing the neurodegenerative condition.

Now, a new international study led by researchers from the University of Gothenburg in Sweden has made a stunning finding: the elevated levels of tau seen in patients with Alzheimer’s disease are also seen in newborns. Understanding why newborns can tolerate high tau phosphorylation without damage to brain cells could help researchers develop treatments that mimic this protective state in older adults with Alzheimer’s. “We believe that understanding how this natural protection works – and why we lose it as we age – could offer a roadmap for new treatments,” said lead and corresponding author Fernando Gonzalez-Ortiz, a doctoral student from the University of Gothenburg’s Department of Psychiatry and Neurochemistry.

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