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Researchers Search For More Precise Ways To Measure Pain


Scientists are developing biomarkers to objectively measure pain, addressing a fundamental medical challenge that has contributed to the opioid crisis and led to consistent underestimation of pain in women and minorities. Four research teams funded by the Department of Health and Human Services ar...

Their approaches include a blood test for endometriosis pain, a device measuring nerve response through pupil dilation, microneedle patches sampling interstitial fluid, and a wearable sensor detecting pain markers in sweat. "When patients are told that the pain is all in their head, the implication is that it's imagined, but the irony is that's sort of right," said Adam Kepecs, a neuroscience professor at Washington University. These innovations could transform treatment for the nearly 25% of Americans suffering from chronic pain, while potentially saving billions in healthcare costs.

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