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Revolutionary Dual Action Antibiotic Makes Bacterial Resistance Nearly Impossible
A new type of antibiotic "targets bacteria in two ways," writes SciTechDaily, which "could make it 100 million times harder for bacteria to develop resistance, according to recent research from the University of Illinois Chicago." Their experiments demonstrate that [a class of synthetic drugs call...
Their experiments demonstrate that [a class of synthetic drugs called] macrolones can work two different ways — either by interfering with protein production or corrupting DNA structure. "The beauty of this antibiotic is that it kills through two different targets in bacteria," said Alexander Mankin, distinguished professor of pharmaceutical sciences at UIC. Fluoroquinolones, such as ciprofloxacin, target a bacteria-specific enzyme called DNA gyrase.... "The main outcome from all of this work is the understanding of how we need to go forward," Mankin said.
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