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Scientists Can Now 3D Print Tissues Directly Inside the Body—No Surgery Needed


A new bioprinter uses ultrasound to non-invasively 3D print tissues, biosensors, and medication depots deep in the body.

But these artificial tissues are printed outside of the body, and they still require additional surgeries to implant, adding to the chances of scarring, inflammation, or infection, and increasing healing time. Dubbed deep tissue in vivo sound printing (DISP), the system uses an injectable bioink that’s liquid at body temperature but solidifies into structures when blasted with ultrasound. “This work has really expanded the scope of ultrasound-based printing and shown its translational capacity,” Yu Shrike Zhang at Harvard Medical School, who was not involved in the research, told IEEE Spectrum.

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