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Scientists discover a new hormone that can build strong bones in mice
A newly discovered hormone explains why females can maintain bone density during lactation, when calcium is stripped away to make milk. This discovery could one day have applications to treating fractures, osteoporosis, and other bone diseases.
Breast cancer survivors taking certain hormone blockers Younger, highly trained elite female athletes Older men whose relative survival rate is poorer than women after a hip fracture The researchers plan to carry out future studies on the molecular mechanisms of CCN3, its levels in breastfeeding women, as well as the potential of the hormone to treat a variety of bone conditions. Muriel Babey, MD, a co-first author and mentored physician-scientist in the Division of Endocrinology at UCSF, is keen to begin asking how CCN3 impacts bone metabolism in clinically relevant disease settings.
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