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Scientists make DNA discovery that could help find pancreatic cancer cure
Hope for new treatments after researchers find spread of disease is aided by shutting down of molecules in key genes
A team of researchers from the UK and US have found that pancreatic cancer is able to shut down molecules in one of the body’s most important genes, helping the disease to grow and spread rapidly. They found pancreatic cancers triggered a process known as DNA methylation, causing molecules in the normally beneficial HNF4A gene to switch off, allowing tumours to grow extremely quickly. “This project gives us new information on how pancreatic cancer is able to suppress certain molecules to help it spread aggressively around the body which, in turn, could lead to the development of more effective treatment options in the future.”
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