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Scientists use bacteria to turn plastic waste into paracetamol


Genetically modified E coli used to create painkillers from material produced from plastic bottles

The team made their discovery when they took polyethylene terephthalate (PET) – a type of plastic often found in food packaging and bottles – and, using sustainable chemical methods, converted it into a new material. When the researchers incubated this material with a harmless strain of E coli they found it was converted into another substance known as Paba in a process that must have involved a Lossen rearrangement. Crucially, while the Lossen rearrangement typically involves harsh laboratory conditions, it occurred spontaneously in the presence of the E coli, with the researchers discovering it was catalysed by phosphate within the cells themselves.

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