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Side-effect-free male contraceptive pill achieves milestone in its human trial


Finally, researchers are closing in on an oral male contraceptive pill that works without hormones, offers full reversibility and – most strikingly – has caused zero side effects. The pill, called YCT-529, which has an entirely new kind of contraceptive mechanism, has passed a critical human safety…

While this is an outstanding outcome for the most promising male contraceptive candidate we have, news coverage of it drew plenty of ire from women who have had to endure a host of side-effects and serious health risks associated with their hormonal birth control methods. Why this new drug from young pharmaceutical startup YourChoice Therapeutics is so promising, however, is that unlike hormonal male contraceptive candidates – which typically lower testosterone and can cause side effects – YCT-529 targets a specific protein: retinoic acid receptor alpha (RARα). Two back-to-back publications demonstrate our commitment to conducting rigorous studies, which strengthens our ability to develop the first hormone-free birth control pill for men efficiently and as expeditiously as possible to meet the growing demand.”

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