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Spectrum of Covid-19: From Asymptomatic Organ Damage to Long Covid Syndrome


Introduction Symptomatic Long COVID affects 10-30% of the COVID-19-infected population depending on what symptoms are measured. (1-3) Organ damage might affect over 50% of post-COVID-19 individuals (4-6) and perhaps more in adolescents and children. (7) As COVID-19 continues to transmit across the world, the consequences of the pandemic are becoming clearer. It is now known … Continued

(56) Inflammation of the Vagus nerve has been observed to cause dysautonomia during acute infection leading to disruption of the autonomic nervous system and affecting heartbeat, blood pressure, digestion, breathing, bladder control, dental health, etc. (92) But It can also lead to an increased risk of hypogonadism and erectile dysfunction,(93,94) negatively affecting sperm quality parameters,(95) and crossing the placental barrier to infect and damage the placenta and fetus potentially several months following birth. Implications of these findings are that several forms of damage lead to a condition similar to accelerated aging, with telomeres, mitochondria, the nervous, vascular, endocrine and immune system all showing decreased capacity and resilience.

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