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Spit to save lives: 15-minute saliva test detects heart failure at home


This device can detect two key biomarkers for heart failure using only a drop of saliva, delivering results in as little as 15 minutes.

“Our device would be ideal for people who are at high risk for heart failure but have limited access to a hospital or a centralized lab,” says Trey Pittman, one of the study authors and a graduate student at Colorado State University. Despite this potential, the widespread adoption of portable saliva tests for heart health has been hindered by complex production methods and a lack of comprehensive data beyond the detection of a single biomarker. Charles Henry’s team at Colorado State University developed this portable testing platform by combining two of their earlier innovations: a saliva-based microfluidic device and a biosensor that detects the biomarker proteins Galectin-3 and S100A7.

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