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Stanford Reverses Cognitive Decline in Alzheimer's with Brain Metabolism Drug
Neuroscientists at Stanford have linked Alzheimer's disease to the disruption of brain metabolism via the kynurenine pathway, which is affected by amyloid plaque and tau proteins. Their research has demonstrated that drugs blocking this pathway can restore cognitive function in Alzheimer's mice b
Stanford researchers have found that blocking the kynurenine pathway in the brain can reverse the metabolic disruptions caused by Alzheimer’s disease, improving cognitive functions in mice. Credit: SciTechDaily.com Neuroscientists at Stanford have linked Alzheimer’s disease to the disruption of brain metabolism via the kynurenine pathway, which is affected by amyloid plaque and tau proteins. The mice performed better in cognitive and memory tests when we gave them drugs that block the kynurenine pathway,” said senior author, Katrin Andreasson, a neurologist at the Stanford School of Medicine and member of the Wu Tsai Neurosciences Institute.
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