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Stem cell therapy trial reverses "irreversible" damage to cornea
Eye injuries that damage the cornea are usually irreversible and cause blindness. But a new clinical trial has repaired this damage in patients thanks to a transplant of stem cells from their healthy eyes.
Since it’s on the frontline of potential hazards from the outside world, the cornea features a population of limbal epithelial stem cells, which repair minor damage to keep the surface smooth and functional. The new study, conducted by scientists at Massachusetts Eye and Ear, investigated a new treatment called cultivated autologous limbal epithelial cells (CALEC). In tests of visual acuity in the damaged eye, the majority of patients regained some sight, with some advancing from legally blind to low vision.
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