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Strange Visual Auras Could Hold the Key to Better Migraine Treatments
Research on the visual patterns that foreshadow migraines may reveal clues on how painful headaches arise from the brain even though it has no pain receptors.
The brain, like other internal organs, is insensate, its lack of sensory receptors attested by videos of virtuoso violinists who play on unfazed as neurosurgeons go to work inside their skulls. Past studies have proposed that migraine headaches occur when something in the cerebrospinal fluid indirectly activates nerves in the nearby meninges, the layers of membrane between the brain and the skull. A dozen of the proteins that increased are known to act as transmitter substances capable of activating sensory nerves, including one called calcitonin gene-related peptide (CGRP), a known target for migraine drugs.
Or read this on Wired