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Technology originating at MIT leads to approved bladder cancer treatment


A system based on a design conceived in Professor Michael Cima’s lab at MIT has been approved by the Food and Drug Administration to treat high-risk, non-muscle-invasive bladder cancer.

In the mid 2000s, Langer connected Cima with a urologist at Boston Children’s Hospital who was seeking a new treatment for a painful bladder disease known as interstitial cystitis. With the problem well-defined, Cima received a grant from MIT’s Deshpande Center for Technological Innovation, which allowed Lee to work on designing a better solution as part of his PhD thesis. The new design was able to slowly release drugs over a two-week period — far longer than any other approach — and could then be removed using a thin, flexible tube commonly used in urology, called a cystoscope.

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