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The Cellular Secret to Resisting the Pressure of the Deep Sea


Cell membranes from comb jellies reveal a new kind of adaptation to the deep sea: curvy lipids that conform to an ideal shape under pressure.

Led by his student Jacob Winnikoff, the interdisciplinary team discovered that the membranes of comb jellies that reside in the depths are made of lipid molecules with completely different shapes than those of their shallow-water counterparts. To study the cell membranes of deep-sea animals, the biochemist Itay Budin (center) joined forces with marine biologists Steve Haddock (right) and Jacob Winnikoff (left). “The composition of the membrane almost restricts the organisms to a particular pressure range,” said Peter Meikle, a lipid biologist who works on plasmalogens at the Baker Heart and Diabetes Institute in Australia and was not involved in the study.

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