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The Most Expensive Eating Disorder
claimer: I have never personally met Bryan. Reading this again, I realized that this article is quite harsh at times.
When body fat gets to very low levels, for evolutionary reasons, people are set to become obsessive, rigid, and engage in OCD-like behaviors intended to help with foraging. Bryan engages in a very intense exercise regimen, has very low body fat levels and therefore great insulin sensitivity(i.e., he can tolerate more carbs as his nutrient-partitioning is presumably excellent), and also takes a very high dose of thyroid hormones. Cortical atrophy has been reported in primate studies looking at the effects of starvation on longevity (I am sure Bryan is aware of this but once you have an eating disorder it is sort of hard to stop…).
Or read this on Hacker News