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The price of genetic analysis has decreased by a factor of 10 million in a decade. It’s astounding what’s happening! - Manolis Kellis

Estimated cost of sequencing the human genome over time since the Human Genome Project.

As the HGP was nearing completion, genome-sequencing pipelines had stabilized to the point that NHGRI was able to collect fairly reliable cost information from the major sequencing centers funded by the Institute. Based on these data, NHGRI estimated that the hypothetical 2003 cost to generate a 'second' reference human genome sequence using the then-available approaches and technologies was in the neighborhood of $50 million. Direct comparisons between commercial versus academic genome-sequencing operations can be particularly challenging because of the many nuances about what each includes in any cost estimates (with such details often not revealed by private companies).

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