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The protein Reelin keeps popping up in brains that resist aging and Alzheimer’s
Early in life, the protein Reelin helps assemble the brain. Later on, it appears to protect the organ from Alzheimer’s and other threats to memory and thinking.
A trio of studies published in the past year all suggest that the protein Reelin helps maintain thinking and memory in ailing brains, though precisely how it does this remains uncertain. There’s growing evidence that Reelin acts as a “protective factor” in the brain, says Li-Huei Tsai, a professor at MIT and director of the Picower Institute for Learning and Memory. This PET image shows the brain of a Colombian man whose memory and thinking remained intact in his late 60s, even though he carried a rare gene variant that nearly always causes Alzheimer's in a person's 40s.
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