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The wonder and controversy of bringing back the dire wolf from extinction | Colossal Biosciences interview


As soon as Colossal Biosciences declared that it brought the dire wolf back from extinction, everyone felt a sense of wonder.

Martin himself, who popularized the dire wolf as Jon Snow’s Ghost in A Song of Ice and Fire, posed for a picture with the pups to be part of a historic scientific achievement. After the announcement yesterday, I interviewed Colossal Biosciences’ CEO Ben Lamm and Beth Shapiro, an evolutionary biologist who specializes in the genetics of ice age animals and plants. We and our collaborators have made a version of the quoll that includes a single change to a protein sequence that evolved in an animal that lives on the other side of the planet that eats toxic cane toads.

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