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This Bag of Cells Could Grow New Livers Inside of People
Donor livers are in short supply for transplants. A startup is attempting to grow new ones in people instead.
The procedure was carried out in Houston on March 25 as part of a clinical trial that will test the experimental treatment in 12 adults with end-stage liver disease. Healthy donor cells can’t be injected directly into a diseased liver because they won’t survive, says Eric Lagasse, chief scientific officer of LyGenesis and a professor of pathology at the University of Pittsburgh. “It is remarkable to identify lymph nodes as a reproducible and fertile bed for the regeneration of a variety of tissues and organs in two different animal species,” Abla Creasey, vice president of therapeutics development at the California Institute for Regenerative Medicine, says of the company’s approach.
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