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Tiny proteins in ‘junk’ DNA promise next obesity drug breakthrough | Using gene-editing tech, researchers have identified "junk" proteins that could lead to next-gen obesity drugs
Tiny "hidden" proteins lurking in DNA once dismissed as junk may hold the key to the next generation of obesity drugs, according to a new study that has uncovered dozens of new fat-regulating molecules using cutting-edge gene-editing technology.
Tiny "hidden" proteins lurking in DNA once dismissed as junk may hold the key to the next generation of obesity drugs, according to a new study that has uncovered dozens of new fat-regulating molecules using cutting-edge gene-editing technology. In their search for a new obesity treatment strategy, researchers from the Salk Institute for Biological Studies in California have used CRISPR/Cas9 gene editing technology to closely examine an understudied class of molecules once thought to be junk: microproteins. are tiny proteins, often made from “small open reading frames” (smORFs) – previously overlooked sections of our DNA once thought to be junk – that can have surprisingly big effects on how the body works.
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