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Unique Combination of Microbes Could Treat Antibiotic-Resistant Infections | Technology Networks


Research identifies 18 bacterial strains that suppress antibiotic-resistant <i>Enterobacteriaceae</i> in mice. These strains may offer a targeted microbial transplant option to reduce infections.

Researchers at Keio University School of Medicine in Tokyo and the Broad Institute of MIT and Harvard have isolated 18 bacterial strains from stool from healthy people that could potentially be a more effective treatment. Subscribe for FREE The findings, which appear today in Nature, could lead to the development of a microbial transplant for patients that manages antibiotic-resistant bacteria in a more targeted way and with fewer side effects than current treatments. Although more work will be needed to shed light on the precise mechanisms underlying how different bacteria compete with each other, the findings suggest that microbial therapeutics could be used to tweak the ecology of the gut and suppress harmful bacterial infections with fewer negative side effects than typical antibiotic treatments.

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