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Using acetaminophen during pregnancy may increase childrens autism and ADHD risk


When children are exposed to acetaminophen—also known by the brand name Tylenol or as paracetamol—during pregnancy, they may be more likely to develop neurodevelopmental disorders including autism and ADHD, according to a new study.

The researchers used the Navigation Guide Systematic Review methodology—a gold-standard framework for synthesizing and evaluating environmental health data—which enabled them to conduct a rigorous, comprehensive analysis that supported evidence of an association between acetaminophen exposure during pregnancy and increased incidence of NDDs. The researchers noted that while steps should be taken to limit acetaminophen use, the drug is important for treating maternal fever and pain, which can also harm children. “We recommend judicious acetaminophen use—lowest effective dose, shortest duration—under medical guidance, tailored to individual risk-benefit assessments, rather than a broad limitation,” they wrote.

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