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Virus-Based Therapy Shrinks Tumors in Skin Cancer Patients | TVEC therapy shrinks tumors in basal cell carcinoma, simplifying surgeries and activating immune responses.
A study highlights the effectiveness of Talimogene laherparepvec (TVEC) for basal cell carcinoma. The virus-based therapy reduced tumor size in 50% of cases, enabled complete tumor regression in a third and activated immune defenses.
A genetically engineered herpes simplex virus designed to selectively infect and kill tumor cells while stimulating the immune system to recognize and attack cancer. TVEC, a genetically modified herpes simplex virus previously approved for treating superficial melanoma metastases, demonstrated promise in reducing tumor size and simplifying surgery. The study underscores TVEC's potential as a pre-surgical (neoadjuvant) therapy for basal cell carcinoma, particularly in cases where conventional surgery poses risks.
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