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Wearable ultrasound? New tech targets trouble spots in the brain | Sonogenetics provides researchers with a precise method to control brain activity.
This breakthrough holds promise for the precise modulation of targeted cell types across various diseased brain regions.
In 2021, Chen and her team introduced Sonogenetics, a method utilizing focused ultrasound to deliver a viral construct containing ultrasound-sensitive ion channels to genetically selected neurons in the brain. In 2022, Chen and her lab members designed and 3D-printed a flexible and versatile device called an Airy beam-enabled binary acoustic metasurface, which allowed them to manipulate ultrasound beams. Chen and her team, including first authors Zhongtao Hu, a former postdoctoral research associate, and Yaoheng (Mack) Yang, individually designed each Airy-beam metasurface to serve as the basis for wearable ultrasound devices tailored for various applications and precise brain locations.
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