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Weekly Parkinson’s injection would be a game-changer for patients | A slow-release Parkinson's injection would mean not taking pills multiple times a day
A once-a-week Parkinson’s injection could replace multiple daily pills, thanks to a new slow-release formulation developed by researchers. It promises easier treatment, fewer missed doses, and better symptom control.
“Levodopa is the gold-standard therapy for Parkinson’s, but its short life span means it must be taken several times a day,” said Professor Sanjay Garg, a pharmaceutical scientist and the study’s corresponding author. They created a liquid formulation using biodegradable polymers that solidifies into a depot(implant) when injected into muscle tissue, triggered by contact with body fluids. They tested multiple batches with varying polymer ratios and found that the optimal formulation contained 26% PLGA (poly-lactic-co-glycolic acid) and 6% Eudragit L-100.
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