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When did human chromosome 2 fuse?(2023)
More and more, it looks like this event happened shortly before a million years ago, in the common ancestors of Neandertal, Denisovan, and African ancestral humans.
The approach relies on the site frequency spectrum of genetic variants across the genome, which is broadly similar to the method developed by Aaron Ragsdale and coworkers to examine ancient population structure. Hu, Wangjie, Hao, Ziqian, Du, Pengyuan, Di Vincenzo, Fabio, Manzi, Giorgio, Cui, Jialong, Fu, Yun-Xin, Pan, Yi-Hsuan, & Li, Haipeng. Ventura, M., Catacchio, C. R., Alkan, C., Marques-Bonet, T., Sajjadian, S., Graves, T. A., Hormozdiari, F., Navarro, A., Malig, M., Baker, C., Lee, C., Turner, E. H., Chen, L., Kidd, J. M., Archidiacono, N., Shendure, J., Wilson, R. K., & Eichler, E. E. (2011).
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