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Whole-Genome Sequencing Will Change Pregnancy
At WIRED Health 2025, Orchid CEO Noor Siddiqui and the genomics pioneer George Church laid out their view of the future of genetic screening.
By analyzing the DNA of different embryos before selecting which one to implant, Orchid says, parents can lower the risk their children grow up affected by conditions with a genetic basis. Siddiqui was speaking with George Church—a pioneer in genomics and a professor of genetics at Harvard Medical School—at the summit in Boston, exploring the promise and potential of whole-genome sequencing. “Even if you restrict to the worst case, so two parents who are both high-risk, then you drop from that 80 percent ceiling to maybe 55 percent.” This can be a greater reduction than can be achieved by having at-risk patients take drugs, she added.
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