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Why does red wine cause headaches? Our research points to a compound found in the grapes’ skin
Opt for a lighter, cheaper red wine if you’re trying to dodge a headache this holiday season.
Tannin is a type of phenolic compound – it’s found in all plants and usually plays a role in preventing disease, resisting predation or encouraging seed dispersal by animals. But there are many other phenolic compoundsin grapes’ skin and seeds besides tannin that make it into red wines from the winemaking process, and are not present in white, so any of them could be a candidate culprit. Compound Chemistry, CC BY-NC-ND So, if something unique in red wine could inhibit ALDH, slowing down that second metabolic step, would that lead to higher levels of acetaldehyde and a headache?
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