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Woman who had pioneering cancer treatment 18 years ago still in remission
Researchers say woman treated for neuroblastoma as a child is longest known survivor after having CAR T-cell therapy
“It’s nice to have such long-term follow-up and to see that even if it was a very early CAR T-cell – and there’s been a lot of work to make them better – we were still able to see a clinical remission that’s been sustained for this long, so that she’s grown up and is leading a normal life,” Heslop says. Writing in the journal Nature Medicine, Heslop and colleagues report how they recruited 19 children to take part in a phase 1 clinical trial of CAR T-cell therapy for neuroblastoma between 2004 and 2009. Karin Straathof, the associate professor in tumour immunology at UCL’s Cancer Institute, who was not involved in the new study, says the results are beyond encouraging.
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