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World-first experimental cancer treatment paves way for clinical trial


An experimental treatment for an aggressive and lethal brain cancer has been published in Nature Medicine, paving the way for a clinical trial by researchers at The Brain Cancer Centre.

An Australian-led international clinical trial will scientifically investigate the efficacy of the approach within a large cohort of eligible glioblastoma patients and could commence within a year. “I am delighted to be handing the baton to Dr Jim Whittle, a leading Australian neuro-oncologist at Peter MacCallum Cancer Centre, The Royal Melbourne Hospital and Co-Head of Research Strategy at The Brain Cancer Centre, to commence a broader scientific study to scientifically determine if – and how – this process might work in treating glioblastoma,” said Prof Long, who also secured drug access for the clinical trial. Dr Whittle, also a laboratory head at WEHI, said: “We are pleased to be able to build on this exciting work by diving into the process of designing a clinical trial, which takes time, care and accuracy.

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